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Figure 1 | BMC Proceedings

Figure 1

From: Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis

Figure 1

Adjustment of systematic variation by normalization using within-pedigree pool and using all individuals pool. a, RMA using a within-pedigree pool: an outlier with systematic variation will be adjusted toward the familial mean of that particular gene expression value. Each symbol (circle, triangle, cross, and X) represents the family and horizontal lines indicate the familial mean value. b, RMA using all individuals as the pool (all subjects shown as circles): an outlier will be adjusted toward the mean of all individuals' gene expression values.

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