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Table 1 Power and type I error of simulations with varying level of heritability for sib pairs

From: Normalizing a large number of quantitative traits using empirical normal quantile transformation

 

Perfect transformation

No transformation

ENQT transformed

Semiparametric QTL

Model

5%

1%

0.10%

5%

1%

0.10%

5%

1%

0.10%

5%

1%

0.10%

a a

4.96

1.02

0.08

11.1

3.63

0.93

4.89

1.05

0.09

2.42

0.98

0.25

b

13.97

3.71

0.51

15.9

5.58

1.62

14.06

3.81

0.51

8.85

3.87

1.32

c

31.69

11.98

2.45

22.92

7.95

1.83

31.55

11.96

2.45

23.72

12.67

5.52

d a

4.69

0.48

0.01

4.68

1.14

0.3

4.71

0.5

0.02

1.94

0.45

0.09

e

11.95

1.96

0.06

7.05

1.62

0.39

11.9

1.94

0.06

6.26

1.91

0.3

f

24.54

6.02

0.39

10.2

2.56

0.67

24.58

5.88

0.38

15.75

5.95

1.67

  1. aThese replicates reflect the null model for which there is no major gene effect.