Distribution of trans -hit along the genome. The x-axis represents the genome order of the 1197 markers. The y-axis represents the number of trans-hits in a 5-Mb neighborhood region of each marker. Markers on different chromosomes are separated by vertical gray lines. The left panel is for the original expression data. The right panel is for the residual analysis with respect to 9p13.3. The positions of DSCR2 (21q22.3) and MAP3k6 (1p36.11), which show strong evidence of trans-linkage to 9p13.3 region, are indicated in the left panel.