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Table 1 Association between SNPs and RA

From: Evaluating gene × gene and gene × smoking interaction in rheumatoid arthritis using candidate genes in GAW15

Candidate gene SNP p-value (11 vs. 12 vs. 22) p-value (11/12 vs. 22)
HAVCRI 5509_5511delCAA 0.066 0.034 a
HAVCRI rs6149307 0.189 0.068
CTLA4 CT60 0.016 0.005
CARD15 HugotSNP12ms3 --b 0.754
CARD15 HugotSNP8ms2 0.838 0.553
CARD15 Hugot_SNP13ms2 -- 0.695
Chr 5 IGR2096ms1 0.473 0.243
Chr 5 IGR3084ms1 0.819 0.713
Chr 5 IGR3138ms1 0.861 0.732
IL3 rs31480 0.618 0.384
SUMO4 rs237025 0.0003 <0.0001
MAP3K7IP2 rs577001 0.002 0.001
MIF rs755622 0.842 0.979
TNFRFF1b rs1061622 0.704 0.684
DLG5 rs1248696 0.269 0.129
SLC22A4 rs2073838 0.904 0.771
PADI4 rs2240340 0.574 0.330
IL4 rs2243250 0.311 0.147
RUNX1 rs2268277 0.55 0.583
PTPN22 rs2476601 <0.0001 <0.0001
  1. Allele "1" is the putative susceptibility allele, and allele "2" is the non-susceptibility allele
  2. aBold text indicates p < 0.05.
  3. b--, Results are not available because there is no homozygote "11" in some groups.