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Table 3 Gene × smoking interactions

From: Evaluating gene × gene and gene × smoking interaction in rheumatoid arthritis using candidate genes in GAW15

  

Ever smoked

    

Marker

Haplotype

No

Yes

ORint

95%CI

p-Value

Empirical p

CT60 (CTLA4)

11

67

58

    
 

12/22

289

393

1.69

1.11, 2.55

0.025

0.023

rs2240340 (PADI4)

11

40

29

    
 

12/22

122

162

2.76

1.24, 6.16

0.026

0.019

IGR3084ms1 (chr 5)

11

23

47

    
 

12/22

327

393

0.59

0.36, 0.97

0.039

0.042

IGR3138ms1 (chr 5)

11

36

69

    
 

12/22

314

374

0.62

0.40, 0.96

0.033

0.04

rs755622 (MIF)

22

234

329

    
 

11/12

120

128

0.73

0.53, 0.99

0.046

0.052