BMC Proceedings

Table 1 Joint genotype probability for a sib pair (genotypes are unordered)

From: Genome-wide linkage and association analysis of rheumatoid arthritis in a Canadian population

	Pr(g₁, g₂)
(g₁, g₂)	Assume HWE	Allow departure from HWE
(0, 0)	$q^{4} + p q^{3} + \frac{1}{4} p^{2} q^{2}$	$P_{0}^{2} + \frac{1}{2} P_{0} P_{1} + \frac{1}{16} P_{1}^{2}$
(0, 1)	pq²(1 + q)	$P_{0} P_{1} + \frac{1}{4} P_{1}^{2}$
(0, 2)	$\frac{1}{2} p^{2} q^{2}$	$\frac{1}{8} P_{1}^{2}$
(1, 1)	pq(1 + pq)	$\frac{1}{2} P_{0} P_{1} + \frac{1}{4} P_{1}^{2} + \frac{1}{2} P_{1} P_{2} + 2 P_{0} P_{2}$
(1, 2)	p²q(1 + p)	$\frac{1}{4} P_{1}^{2} + P_{1} P_{2}$
(2, 2)	$\frac{1}{4} p^{2} q^{2} + p^{3} q + p^{4}$	$\frac{1}{16} P_{1}^{2} + \frac{1}{2} P_{1} P_{2} + P_{2}^{2}$

Back to article page

ISSN: 1753-6561

Contact us

Submission enquiries: supplements@biomedcentral.com
General enquiries: ORSupport@springernature.com