Skip to main content

Table 1 Power to identify the true susceptibility loci using different methods to infer phases

From: Dealing with missing phase and missing data in phylogeny-based analysis

 

% Power (95% confidence interval)

Method

Phaseda

Most likely haplotypesb

Imputationc

2 sites

81 (73.3–88.7)

84 (76.8–91.2)

78 (69.9–86.1)

1 site onlyd

12 (5.6–18.4)

8 (2.7–13.3)

13 (6.4–19.6)

1 site + 1 error

7 (2.0–12.0)

8 (2.7–13.3)

9 (3.4–14.6)

  1. a The phase given in the data is used.
  2. b The phase is inferred using ZAPLO (selection of the most likely haplotypes).
  3. c The phase is inferred using ZAPLO and multiple imputation.
  4. d Only one site has a V i > 0 and it is a true DS site.