Exhaustive screens for disease susceptibility loci incorporating statistical interaction of genotypes: a comparison of likelihood-ratio-based and Akaike and Bayesian information criteria-based methods

Table 1 Candidate SNP markers

HLA Region	r² (DR)^a	Flanking Locus D	q-arm
denseSNP6_3241^b	0.608	denseSNP6_3915	denseSNP6_11568	denseSNP6_15916
denseSNP6_3426^c	0.449	denseSNP6_3916	denseSNP6_11611	denseSNP6_11656
denseSNP6_3271	0.404	denseSNP6_3917	denseSNP6_11621	denseSNP6_15886
denseSNP6_3436^c	0.030	denseSNP6_3918	denseSNP6_15881	denseSNP6_11596
denseSNP6_3281	0.020		denseSNP6_15976	denseSNP6_15961
denseSNP6_3236	0.006		denseSNP6_15921
denseSNP6_3261^b	0.003		denseSNP6_16891
denseSNP6_3251	0.003		denseSNP6_11646
denseSNP6_3476^c	0.001		denseSNP6_11666
denseSNP6_3201^c	0.001		denseSNP6_11616

^aThe diallelic r² with DR C allele.
^bMarginally significant at the study-wide level in over 50% of replicates.
^cMarginally significant at the genome-wide level in over 50% of the replicates.

ISSN: 1753-6561