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Table 2 Simulation results

From: The impact of complex informative missingness on the validity of the transmission/disequilibrium test (TDT)

  Missing patterns Chromosome 15 (type I error: SNP15_55) Chromosome 6 (power: SNP6_150)
Model (Pf11, Pf12, Pf22)(Pm11, Pm12, Pm22)(Po11, Po12, Po22) TDT 1-TDT HRR EM-HRR TDT 1-TDT HRR EM-HRR
1 (0.2,0.2,0.2) (0.2,0.2,0.2) (0.2,0.2,0.2) 5.3 4.8 5.2 4.5 21.5 25.7 22.6 27.9
2 (0.4,0.2,0.2) (0.4,0.2,0.2) (0.1,0.1,0.1) 4.7 16.5 5.8 19.7 21 67.1 22.3 73.9
2 (0.4,0.4,0.2) (0.4,0.4,0.2) (0.1,0.1,0.1) 5.8 14.3 4.4 12 13.8 43.7 11.9 42
2 (0.4,0.3,0.2) (0.4,0.3,0.2) (0.1,0.1,0.1) 5.1 14.4 4.5 16.2 15.9 58 15.7 60.7
2 (0.2,0.2,0.4) (0.2,0.2,0.4) (0.1,0.1,0.1) 4.3 5.1 4.6 6.2 20.1 20.9 21.5 20.7
2 (0.2,0.4,0.4) (0.2,0.4,0.4) (0.1,0.1,0.1) 4.5 6.4 4.1 8.9 15.4 7.7 12.9 5
2 (0.2,0.3,0.4) (0.2,0.3,0.4) (0.1,0.1,0.1) 5.1 6.9 5.3 8.6 17.3 12.6 16.4 10.9
3 (0.4,0.2,0.2) (0.4,0.2,0.2) (0.4,0.2,0.2) 9.5 3.6 10.8 5.5 4.9 21.7 5.5 27.4
3 (0.4,0.4,0.2) (0.4,0.4,0.2) (0.4,0.4,0.2) 9.6 4.2 8.5 4.7 7.9 20.2 7 19.7
3 (0.4,0.3,0.2) (0.4,0.3,0.2) (0.4,0.3,0.2) 8.6 3.4 8.6 4.4 6 18.6 6.1 22.1
3 (0.2,0.2,0.4) (0.2,0.2,0.4) (0.2,0.2,0.4) 10 5.4 11.9 7 34.1 24.8 36.8 29.9
3 (0.2,0.4,0.4) (0.2,0.4,0.4) (0.2,0.4,0.4) 13.5 4.7 12.2 5 41.7 22.2 39.5 23.1
3 (0.2,0.3,0.4) (0.2,0.3,0.4) (0.2,0.3,0.4) 11.5 3.8 11.6 3.6 40.1 23.5 39.7 26.4
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BMC Proceedings

ISSN: 1753-6561

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