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Table 1 Results for selected candidate genes

From: Case-control studies with affected sibships

    GAW data set  
  Allele frequency FST   p-value   
Gene/marker Case Control ANOVA ANOVA no linkage χ2-test p-valuea
PTPN22/rs2476601 0.17 0.08 0.25 <0.0001 <0.0001 <0.0001 <0.0001
CTLA4/CT60 0.39 0.45 0.23 0.0051 0.0054 0.0019 0.0010
HAVCR1/5509_5511delCAA 0.20 0.23 0.22 0.0223 0.0241 0.0117 0.99
SUM04/rs237025 0.51 0.46 0.25 0.0022 0.0026 0.0008 0.99
SUM04/rs577001 0.39 0.35 0.23 0.0280 0.0323 0.0166 -
  1. aOne-sided p-values for the allelic χ2 test given by Plenge et al. If the association was not concordant to previous studies, these p-values were set to 0.99 [6].