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Table 1 Single-marker analysis for SNPs in PTPN22

From: Case-control association analysis of rheumatoid arthritis with candidate genes using related cases

   Minor Allele Frequencies p-valuesa
   Cases Controls   
SNP dbSNP ID Affected Siblingb (n = 1256) One Sibling per Familyc (n = 664) (n = 1519) Affected Siblingb One Sibling per Familyc
1 rs3789604 0.198 0.199 0.179 0.10251 0.11214
2d rs3811021 0.199 0.200 0.179 0.0978 0.10504
3 rs1217413 0.269 0.267 0.217 7 × 10-5 0.00039
4d Ss38346942 0.015 0.015 0.013 0.68537 0.63067
5 rs1217388 0.292 0.293 0.251 0.00233 0.00436
6 Ss38346943 0.017 0.020 0.027 0.03122 0.13409
7 rs1310182 0.491 0.495 0.430 5 × 10-5 7 × 10-5
8d Ss38346944 0.03 0.031 0.023 0.19819 0.15854
9d rs2476601 0.154 0.160 0.084 4.32 × 10-13 8.53 × 10-13
10 rs12730735 0.268 0.270 0.295 0.04785 0.09262
11d rs11102685 0.091 0.085 0.076 0.0629 0.32266
12 rs12760457 0.267 0.269 0.294 0.04884 0.09406
13 rs2488458 0.292 0.293 0.252 0.00257 0.00472
14d rs1217414 0.243 0.236 0.276 0.01283 0.00526
  1. ap-Values were not adjusted for the multiple testing.
  2. bAllele frequencies and p-values were obtained using all cases and unrelated controls.
  3. cAllele frequencies and p-values obtained using one randomly selected case per family and unrelated controls.
  4. dSNPs selected from the stepwise regression.