Table 2 Type I error rates and power (in percentage)for testing linkage or association (T3)
From: Joint modeling of linkage and association using affected sib-pair data
LD group (number of SNPs) | ||||||
|---|---|---|---|---|---|---|
Significance level (%) | r2 = 0, θ = 0.5 (n = 6597) | 0 <r2 <= 0.01 (n = 1751) | 0.01 <r2 <= 0.1 (n = 304) | 0.1 <r2 <= 0.3 (n = 29) | 0.3 <r2 <= 0.92 (n = 18) | |
FBAT | 5 | 5 | 34.8 | 92.1 | 100 | 100 |
1 | 1 | 23.7 | 88.4 | 100 | 100 | |
0.1 | 0.1 | 15 | 82.6 | 100 | 100 | |
Millstein-a | 5 | 5 | 99.2 | 100 | 100 | 100 |
1 | 1 | 98.2 | 100 | 100 | 100 | |
0.1 | 0.1 | 96.3 | 99.9 | 100 | 100 | |