Table 2 Mean LOD scores for the three tests summarized from 100 replicates
Test for linkage | Test for association in the presence of linkage | Test for other linked variants | ||
|---|---|---|---|---|
Models compared | LE vs. BM | GM vs. LE | GM vs. LD | |
d.f. | 4 - 1 = 3 | 5 - 4 = 1 | 5 - 3 = 2 | |
SNP6_153 | With flanking markers | Without flanking markers | ||
ASPs+controls | 705.3 (range: 653.1–763.0) | 7.8 (range: 2.2–17.9) (powera: 100%) | 6.8 (range: 1.8–15.5) (power: 100%) | |
ASPs | 132.3 (range: 105.9–152.9) | 441.9 (range: 401.3–485.8) | 4.1 (range: 0.8–12.6) (power: 94%) | 1.7 (range: 0.0–5.3) (power: 53%) |
SNP6_162 | ||||
ASPs+controls | 44.4 (range: 30.0–62.2) | 59.1 (range: 39.5–81.1) (power: 100%) | 2.0 (range: 0.0–6.3) (power: 63%) | |
ASPs | 9.1 (range: 3.4–15.8) | 27.8 (range: 14.8–41.3) | 58.9 (range: 39.7–81.0) (power: 100%) | 1.8 (range: 0.0–6.1) (power: 55%) |