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Table 1 Results from linkage and association tests between DRB1 and RA, and for oversharing on 6p21

From: No evidence for multiple loci affecting rheumatoid arthritis risk on chromosome 6p21

 

Sample

 

NARAC (452 ASP)

UK (309 ASP)

LOD score at DRB1 locus (p-value)

14.36 (p = 4.28 × 10-16)

4.28 (p = 9.01 × 10-6)

RA odds ratio for each DRB1 high-risk allele (p-value)

18.2 (p < 0.0001)

N/Aa

Sun method T statistic (p-value)

T = -0.2 (p = 1)

T = -0.6 (p = 1)

  1. aNot applicable because all genotyped individuals in the UK sample are affected.