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Table 1 Parameter settings for simulating disease models

From: A logistic mixture model for a family-based association study

Disease modela f 0 b f 1 b f 2 b p D c Prevalence
D3 0.010 0.030 0.030 0.300 0.020
D6 0.010 0.060 0.060 0.300 0.036
D9 0.010 0.090 0.090 0.300 0.051
R3 0.010 0.010 0.030 0.300 0.012
R6 0.010 0.010 0.060 0.300 0.015
R9 0.010 0.010 0.090 0.300 0.017
A3 0.010 0.020 0.030 0.300 0.016
A6 0.010 0.035 0.060 0.300 0.025
A9 0.010 0.050 0.090 0.300 0.034
  1. aD, R and A denote (for the minor allele) dominant, recessive, and additive modes of inheritance, respectively.
  2. bf j denotes the penetrance of a genotype with j disease-predisposing alleles.
  3. cDisease-predisposing allele frequency.