Skip to main content

Advertisement

Table 2 Empirical type I error rate at a nominal 0.05 significance level and power at an estimated 0.05 significance level under various assumed genetic models, based on 500 replicate samples

From: A logistic mixture model for a family-based association study

  Analysis model
  Dominant Recessive Additive
  SEGREG ASSOC SEGREG ASSOC SEGREG ASSOC
Simulation model Type I error Power Type I error Power Type I error Power Type I error Power Type I error Power Type I error Power
D3 0.006 0.828 0.006 0.818 0.014 0.074 0.010 0.080 0.000 0.530 0.000 0.524
D6 0.016 0.988 0.016 0.986 0.030 0.062 0.018 0.056 0.004 0.852 0.004 0.824
D9 0.004 1.000 0.004 1.000 0.022 0.058 0.022 0.068 0.004 0.940 0.002 0.914
R3 0.004 0.036 0.004 0.036 0.030 0.646 0.024 0.706 0.006 0.450 0.004 0.468
R6 0.008 0.030 0.010 0.028 0.020 0.998 0.022 1.000 0.002 0.978 0.004 0.982
R9 0.016 0.064 0.016 0.056 0.018 1.000 0.018 1.000 0.010 0.996 0.012 1.000
A3 0.012 0.468 0.012 0.462 0.022 0.232 0.020 0.250 0.001 0.552 0.002 0.546
A6 0.008 0.844 0.008 0.838 0.030 0.324 0.022 0.352 0.012 0.874 0.012 0.854
A9 0.010 0.944 0.014 0.936 0.016 0.550 0.010 0.574 0.001 0.962 0.004 0.960