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Table 1 Chromosomal regionsa

From: Comparison of tagging single-nucleotide polymorphism methods in association analyses

Chr (Mb)

Size (kb)

N SNPsb

Mean r2

Protein (Probe set)

Original SNPc

Cheung et al. [7] p-value

Current p-valued

5 (96)

68

72

0.65

LRAP (219759_at)

rs2762

2.0 × 10-19

8.0 × 0-11

6 (32)

90

52

0.20

HLA-DRB2 (209480_at)

rs6928482

6.5 × 10-11

3.8 × 10-7

20 (33)

49

44

0.58

CPNE1 (206918_s_at)

rs6060535

8.4 × 10-13

1.3 × 10-7

20 (36)

25

16

0.73

AA827892 (65588_at)

rs788350

3.7 × 10-15

1.6 × 10-5

21 (44)

42

26

0.40

CSTB (201201_at)

rs880987

2.5 × 10-12

6.5 × 10-6

  1. aRegions defined as ± 5 kb surrounding original SNP and cis gene.
  2. bBased on MAF > 0.05 in CEU HapMap release 21.
  3. crs Identification number shown is that reported by Cheung et al. based on 57 CEU founders [7].
  4. dCurrent p-value based on 28 CEU founders.