Table 2 Single-SNP association resultsa
From: Comparison of tagging single-nucleotide polymorphism methods in association analyses
| Â | LRAP | HLA-DRB2 | CPNE1 | AA827892 | CSTB | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | N b | min(p)c | N | min(p) | N | min(p) | N | min(p) | N | min(p) |
All SNPs | 72 | 8.0 × 10 -11 | 52 | 3.4 × 10 -11 | 44 | 1.3 × 10 -7 | 16 | 1.5 × 10 -5 | 26 | 6.5 × 10 -6 |
ldSelect | 9 | 3.6 × 10 -7 | 28 | 3.4 × 10 -11 | 3 | 1.3 × 10 -7 | 3 | 3.7 × 10 -5 | 9 | 5.4 × 10 -5 |
TagSNPs-Rspair | 10 | 1.3 × 10 -7 | 20 | 1.8 × 10 -5 | 3 | 1.3 × 10 -7 | 4 | 1.5 × 10 -5 | 9 | 5.4 × 10 -5 |
TagSNPs-Rspair-trios | 10 | 1.3 × 10 -7 | 20 | 1.8 × 10 -5 | 3 | 1.3 × 10 -7 | 4 | 1.5 × 10 -5 | 9 | 6.5 × 10 -6 |
Tagger-pairwise | 9 | 2.2 × 10 -8 | 26 | 1.2 × 10 -8 | 3 | 1.2 × 10 -5 | 3 | 3.7 × 10 -5 | 9 | 4.8 × 10 -5 |
TagSNPs-Rs | 5 | 1.1 × 10 -8 | 9 | 3.4 × 10 -11 | 2 | 3.2 × 10-2 | 3 | 5.9 × 10-2 | 4 | 9.9 × 10 -3 |
TagSNPs-Rs-trios | 5 | 1.1 × 10 -8 | 9 | 1.4 × 10 -5 | 2 | 2.9 × 10-2 | 3 | 5.9 × 10-2 | 4 | 9.9 × 10 -3 |
Tagger-multimarker | 7 | 3.6 × 10 -7 | 18 | 3.4 × 10 -11 | 3 | 1.3 × 10 -7 | 3 | 3.7 × 10 -5 | 9 | 4.8 × 10 -5 |
TagSNPs-Rh | 7 | 2.8 × 10 -9 | 9 | 3.8 × 10 -7 | 2 | 1.2 × 10 -5 | 3 | 1.5 × 10 -5 | 4 | 9.9 × 10 -3 |
TagSNPs-Rh-trios | 6 | 3.6 × 10 -7 | 8 | 5.1 × 10 -5 | 2 | 1.2 × 10 -5 | 3 | 1.5 × 10 -5 | 4 | 1.5 × 10-2 |