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Table 1 Genotype-based classification of subjects with respect to IgM levels

From: Modeling activation of inflammatory response system: a molecular-genetic neural network analysis

IgM level

N

Prevalence

Normal

Low

Elevated

Sensitivity

Specificity

Normal

576

62.2%

576 a

0

0

0.988

0.997

Low

237

25.6%

1

184

52

0.776

0.987

Elevated

113

12.2%

0

2

111

0.982

0.936

  1. Neural Network Analysis yielded weights that enabled re-classification of 926 subjects with respect to IgM levels through genotype-based classifiers at a sensitivity and specificity of >90% (with the exception of 23.4% of low IgM level subjects who were classified as subjects with elevated IgM levels).
  2. aBold text indicates correctly re-classified subjects prior to k-fold cross-validation.