IgM level
|
N
|
Prevalence
|
Normal
|
Low
|
Elevated
|
Sensitivity
|
Specificity
|
Normal
|
576
|
62.2%
|
576
a
|
0
|
0
|
0.988
|
0.997
|
Low
|
237
|
25.6%
|
1
|
184
|
52
|
0.776
|
0.987
|
Elevated
|
113
|
12.2%
|
0
|
2
|
111
|
0.982
|
0.936
|
- Neural Network Analysis yielded weights that enabled re-classification of 926 subjects with respect to IgM levels through genotype-based classifiers at a sensitivity and specificity of >90% (with the exception of 23.4% of low IgM level subjects who were classified as subjects with elevated IgM levels).
- aBold text indicates correctly re-classified subjects prior to k-fold cross-validation.