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Table 1 Summary of significant associations (p < 0.05) between RA and candidate genes

From: Classification of rheumatoid arthritis status with candidate gene and genome-wide single-nucleotide polymorphisms using random forests

  Single-gene model Multiple-gene model
Gene*SNP Carrier-test Genotype-test p-Value OR (95% CI)
PTPN22*rs2476601 <0.0001 <0.0001 <0.0001 2.43 (1.82, 3.24)
CTLA4*CT60 0.0060 0.0172 0.0115 0.72 (0.56, 0.93)
HAVCR1*5509_5511delCAA 0.0339 0.0640 0.0731 0.80 (0.63, 1.02)
SUM04*rs237025 <0.0001 0.0002 0.1044 1.39 (0.94, 2.04)
MAP3K71P2*rs577001 0.0012 0.0017 0.4527 1.14 (0.80, 1.63)