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Table 1 The number of GA evaluations to obtain one of the ten most significant interactions

From: Identification of expression quantitative trait loci by the interaction analysis using genetic algorithm

  SNP1 SNP2    
Expressed gene rs number Gene Chr rs number Gene Chr p-Value Generations Evaluations
EP300 rs1037782 LOC441716 15q13.1 rs1274224 ZBTB20 3q13.2 8.97 × 10-7 11 11000
  rs616113 CACNA2D3 3p21.1 rs312926 BRUNOL5 19p13 2.01 × 10-6 20/8a 20000/8000a
  rs1909160   12 rs1824780   5 2.23 × 10-6 28/7/37a 28000/7000/37000a
  rs2219328   3 rs721602   12 2.46 × 10-6 7 7000
  rs1909160   12 rs1463234   3 4.33 × 10-6 9/46a 9000/46000a
  rs627953   18 rs1537375 LOC401495 9 9.89 × 10-6 15 15000
BRCA1 rs1037782   15 rs1274224 ZBTB20 3q13.2 8.97 × 10-7 26/27/11/21a 26000/27000/11000/21000a
  rs1025048   5 rs1430509   4 4.33 × 10-7 22/12a 22000/12000a
  rs1861478   12 rs1391708   12 7.47 × 10-7 46 46000
  rs2215054 KIAA0672 17p12 rs179562   14 8.15 × 10-7 6 6000
  rs2215054 KIAA0672 17p12 rs593418   18 4.01 × 10-7 10 10000
  rs2215054 KIAA0672 17p12 rs179562   14 8.15 × 10-7 38 38000
TAF15 rs2180052   6 rs1798294   12 8.49 × 10-9 74/12a 74000/12000a
  rs1798294   12 rs564021   18 4.11 × 10-9 33 33000
  rs1798294   12 rs1480691 SGCZ 8p22 1.6 × 10-9 32 32000
  rs766083 FER1L3 10q24 rs2040692   22 5.53 × 10-9 68 68000
  rs1798294   12 rs1524163 NR5A2 1q32.1 5.43 × 10-9 12 12000
  rs1798294   12 rs1548543   19 6.21 × 10-10 25/11/11/40a 25000/11000/11000/40000a
  1. aSNP pairs are identified from more than two runs.