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Table 1 Distribution of the number of expression phenotypes with different number of SNPs in the regression models of steps 1 and 3 of our three-step method

From: Identifying cis- and trans-acting single-nucleotide polymorphisms controlling lymphocyte gene expression in humans

Step No. SNPs 0 1 2 3 4 5 6 7 8 9 ≥10
1 Availablea 1286 413 310 614 417 148 169 59 16 16 14
  AICb 1286 1697 350 107 17 3 1 1 0 0 0
  p ≤ 0.01c   245 43 0 0 0 0 0 0 0 0
  p ≤ 0.001c   88 5 0 0 0 0 0 0 0 0
3 Linkagesd 294 81 76 118 141 102 101 102 110 91 2264
  AIC 294 664 362 295 270 236 187 147 127 101 645
  p ≤ 0.01c   930 433 188 101 58 38 21 11 11 32
  p ≤ 0.001c   572 151 60 25 12 10 3 6 2 2
  1. a"Available" denotes the number of phenotypes with the given number of available cis-SNPs in Step 1.
  2. b"AIC" denotes the number of phenotypes where the given number of SNPs was retained by the stepwise linear regression model.
  3. cThe number of phenotypes among those in the previous line in which the p-values of SNP associated with the phenotypes are less than or equal to the given significance level.
  4. d"Linkages" denotes the number of phenotypes linked (LOD > 2.0) to the given number of SNPs.