Table 1 Expression phenotypes with the strongest agreement and evidence of linkage for the Morley et al. [2], single-probe, and principal-components analyses
From: Linkage analysis using principal components of gene expression data
| Â | Â | Â | Morley et al. [2] | Single probe | Principal components | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Gene | Location | Probe | p-value | LOD | p-value | Position (cM) | PC | LOD | p-value | Position (cM) |
CH13L2 | 1p13.3 | 213060.s.at | <10-10 | 11.6 | <10-12 | 111.8 | 3 | 2.9 | <10-3 | 112.2 |
ZP3 | 7q11 | 210910.at | <10-9 | 13 | <10-14 | 75.6 | 4 | 2.9 | <10-3 | 64.3 |
PSPHL | 7p11 | 205048.s.at | <10-10 | 6.1 | <10-7 | 64.3 | 4 | 2.9 | <10-3 | 64.3 |
DDX17 | 22q13 | 208151x.at | <10-9 | 5.9 | <10-7 | 43.4 | 5 | 1.2 | <10-2 | 47.7 |
UGT2B17 | 4q13 | 207245.at | --------- | 8.3 | <10-9 | 62.3 | 2 | 7.1 | <10-8 | 63.9 |
LRAP | 5q15 | 219759.at | --------- | 8.1 | <10-9 | 99 | 4 | 5.6 | <10-6 | 97.7 |
HLA-DQB1 | 6p21.3 | 209480.at | --------- | 9 | <10-10 | 36 | 1 | 10.7 | <10-11 | 34.2 |
HLA-DPB1 | 6p21.3 | 201137.s.at | --------- | 8.8 | <10-10 | 31.6 | 3 | 3.8 | <10-4 | 38.3 |