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Table 1 Results of latent class analysis of linkage

From: Genetic heterogeneity and trans regulators of gene expression

   

Class 1 "unlinked" families

Class 2 "linked" families

Phenotype

Chromosome with trans peak

Marginal (One-class) slope (p-value)

Slope

No. of families in Class 1

Slope (p-value)

No. of families in Class 2

ALG6

19

-0.04 (<0.001)

-0.01

12

-0.17 (<0.001)

2

CBR1

15

-0.67 (0.002)

0.12

11

-3.10 (<0.001)

3

DSCR2

9

-0.07 (<0.001)

-0.02

11

-0.27 (0.015)

3

HOMER1

9

-0.42 (<0.001)

-0.13

11

-1.31 (<0.001)

3

TNFRSF11A

3

-0.93 (0.067)

0.08

12

-4.04 (0.001)

2

  1. "Linked" and "unlinked" families were identified for the five expression phenotypes that showed strongest evidence of linkage in trans.