Table 1 19 gene expression phenotypes with genome-wide significant linkage evidence after correcting for multiple tests
From: A genome-wide linkage study of GAW15 gene expression data
| Â | Â | Merlin VC LOD | Linkage peak position | Â | SIBPAL linkage | |||
|---|---|---|---|---|---|---|---|---|
Genea | Location | log2-transformed | not log2-transformed | Chr | position (cM) | h 2 | log2-transformed | not log2-transformed |
LOC388796 | 20q11 | 14.65 | 13.92 | 20 | 59.3 | 0.66 | 2.9 × 10-13 | 7.4 × 10-13 |
ZP3 | 7q11 | 13.91 | 13.34 | 7 | 84.5 | 0.87 | 1.1 × 10-16 | 4.4 × 10-14 |
CHI3L2 | 1p13 | 13.06 | 12.72 | 1 | 119.2 | 0.75 | <10-16 | <10-16 |
LRAP | 5q15 | 11.38 | 8.51 | 5 | 105 | 0.58 | <10-16 | 4.4 × 10-16 |
DDX17 | 22q13 | 11.36 | 10.3 | 22 | 49.8 | 0.59 | 3.0 × 10-11 | 4.4 × 10-12 |
PSPH | 7p15 | 10.99 | 8.74 | 7 | 78.7 | 0.64 | 5.0 × 10-9 | 5.2 × 10-5 |
UGT2B17 | 4q13 | 9.62 | 3.43 | 4 | 74.8 | 0.62 | 2.7 × 10-5 | 0.03 |
HLA-DPB1 | 6p21 | 8.87 | 8.8 | 6 | 49.7 | 0.7 | 5.0 × 10-6 | 3.2 × 10-5 |
ITGB1BP1 | 2p25 | 8.25 | 8.31 | 2 | 25.5 | 0.66 | 4.4 × 10-11 | 2.1 × 10-10 |
CSTB | 21q22 | 7.39 | 7.54 | 21 | 85.4 | 0.49 | 7.4 × 10-10 | 7.0 × 10-9 |
PPAT | 4q12 | 6.72 | 6.65 | 4 | 66.7 | 0.36 | 2.8 × 10-8 | 4.8 × 10-8 |
IRF5 | 7q32 | 6.08 | 6.32 | 7 | 124.2 | 0.51 | 3.1 × 10-15 | 1.8 × 10-14 |
PEX6 | 6p21 | 5.86 | 5.67 | 6 | 56.4 | 0.63 | 2.1 × 10-5 | 9.2 × 10-7 |
RPL31 | 2q11 | 5.77 | 5.87 | 2 | 116.3 | 0.22 | 5.2 × 10-11 | 4.9 × 10-14 |
PYGB | 20p11 | 5.66 | 3.96 | 4 | 55.6 | 0.67 | 0.085 | 0.38 |
HSD17B12 | 11p11 | 5.51 | 5.49 | 11 | 50.6 | 0.55 | 1.1 × 10-10 | 6.7 × 10-16 |
GSTM1 | 1p13 | 5.49 | 5.14 | 1 | 118.3 | 0.68 | 7.8 × 10-7 | 5.0 × 10-5 |
GSTM2 | 1p13 | 5.31 | 5.15 | 1 | 119.16 | 0.42 | 3.7 × 10-6 | 1.5 × 10-5 |
TMED10 | 14q24 | 5.31 | 5.27 | 4 | 56.3 | 0.58 | 0.12 | 0.08 |