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Table 2 Highest LOD score or log (Bayes factor) and run time (in minutes)

From: Comparison of multipoint linkage analyses for quantitative traits in the CEPH data: parametric LOD scores, variance components LOD scores, and Bayes factors

    CHI3L2 147 cM (chr 1)a GSTM1 142 cM (chr 1) PSPH 80 cM (chr 7) VAMP8 113 cM (chr 2)
Model Program Scans Statb Time Stat Time Stat Time Stat Time
1Q Exact NA 11.5 1229 6.3 1234 10.1 470 3.6 1044
  lm_multiple 3 k 11.3–11.5 44 6.2–6.3 45 9.9–10.1 33 3.6–3.6 43
  lm_markers 3 k 10.7–11.6 21 5.7–6.3 21 8.1–10.3 13 3.5–3.6 20
  lm_markers 30 k 10.6–11.6 177 5.7–6.3 168 8.1–10.1 110 3.2–3.6 153
1Q + P lm_twoqtl 30 k 13.7 563 7.2 604 10.8 401 3.8 535
1Q + UQ lm_twoqtl 3 k 13.4 3568 5.6 816 40.4 542 4.1 808
VC Merlin NA 13 2 5.7 2 14.3 1 5 2
Bayesian Loki 999 k 2.9 707 2.6 700 2.6 504 1.9 513
  1. apeak position (± 1 cM) from all analyses and gene location except VAMP8 (120–123 cM).
  2. bMORGAN and VC programs, the statistic (stat) is the LOD score with range (min and max) over 10 runs and time is the median of 10 runs for MCMC programs; Loki, stat is the log10 (Bayes factor) for one run.