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Table 2 Highest LOD score or log (Bayes factor) and run time (in minutes)

From: Comparison of multipoint linkage analyses for quantitative traits in the CEPH data: parametric LOD scores, variance components LOD scores, and Bayes factors

   

CHI3L2 147 cM (chr 1)a

GSTM1 142 cM (chr 1)

PSPH 80 cM (chr 7)

VAMP8 113 cM (chr 2)

Model

Program

Scans

Statb

Time

Stat

Time

Stat

Time

Stat

Time

1Q

Exact

NA

11.5

1229

6.3

1234

10.1

470

3.6

1044

 

lm_multiple

3 k

11.3–11.5

44

6.2–6.3

45

9.9–10.1

33

3.6–3.6

43

 

lm_markers

3 k

10.7–11.6

21

5.7–6.3

21

8.1–10.3

13

3.5–3.6

20

 

lm_markers

30 k

10.6–11.6

177

5.7–6.3

168

8.1–10.1

110

3.2–3.6

153

1Q + P

lm_twoqtl

30 k

13.7

563

7.2

604

10.8

401

3.8

535

1Q + UQ

lm_twoqtl

3 k

13.4

3568

5.6

816

40.4

542

4.1

808

VC

Merlin

NA

13

2

5.7

2

14.3

1

5

2

Bayesian

Loki

999 k

2.9

707

2.6

700

2.6

504

1.9

513

  1. apeak position (± 1 cM) from all analyses and gene location except VAMP8 (120–123 cM).
  2. bMORGAN and VC programs, the statistic (stat) is the LOD score with range (min and max) over 10 runs and time is the median of 10 runs for MCMC programs; Loki, stat is the log10 (Bayes factor) for one run.