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Table 2 Summary of studies.

From: Comparison of analyses of the QTLMAS XII common dataset. II: genome-wide association and fine mapping

Study

Type

Loci

Type of locia

Loci effects

Additional effects

Model

Comments

LABayes [7]

LA

multiple

multi-markerb

fixed, additive

sex + generation

Bayesian

only every tenth marker used

LDBayes [8]

LD

multiple

single marker

random, additive

-

Bayesian

 

LDLA1 [9]

LD

multiple

single marker

fixed, additive +dominance

polygenic

mixed model, REMLc and FSd

markers selected by allele frequency difference in high/low offspring per sire

 

LDLA

single

haplotype (2)

random, additive

polygenic

variance component, REML

markers selected by allele frequency difference in high/low offspring per sire

LDmulti [10]

LD

multiple

single marker

fixed, additive +dominance +epistasis

pre-correction for polygenic + sex + generation

linear regression, least squares and FS

mixed model, REML used for pre-correction

LDHap [11]

LD

single

haplotype (10e)

fixed, additive

pre-correction for polygenic + sex + generation

phylogeny building, cluster analysisf

mixed model, MLg for pre-correction, maximum in 10 cM interval

 

LD

single

single marker

fixed, additive

polygenic + sex + generation

mixed model, ML

maximum in 5 cM interval, explored epistasis

LDLA2 [12]

LA

two

single marker

random, additive

polygenic

variance component, REML

only marker data from last two generations used

 

LDLA

single

haplotype (10)

random, additive

polygenic

variance component, REML

only marker data from last two generations used, only on most significant region per chromosome from LA

 

LD

single

haplotype (3)

random, additive

polygenic

variance component, REML

only marker data from last two generations used, only on most significant region per chromosome from LA

  1. aIn brackets is the number of markers in a haplotype. bProbability of QTL genotype is conditional on all marker data (at reduced 1 cM density) for the chromosome. cRestricted maximum likelihood. dForward selection. eAt least 10 markers used. fUsing Blossoc [16]. gMaximum likelihood.