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Figure 3 | BMC Proceedings

Figure 3

From: Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation

Figure 3

The relationship of POG with the sample size: (A) 50 samples/group and (B) 5 samples/group. The simulated datasets had CV = 30% and magnitude = 50 (see Table 1). The x-axis represents the number of genes selected as differentially expressed, and the y-axis represents the POG (%) of two gene lists for a given number of differentially expressed genes. Each line on the graph represents the overlap of differentially expressed gene lists based on one of six different gene ranking/selection methods. The red and blue numbers give the POG (%) when 500 genes (red dashed line) are selected as DEGs using P rank ordering only and FC rank ordering with P < 0.05, respectively.

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