From: A synopsis of eukaryotic Nα-terminal acetyltransferases: nomenclature, subunits and substrates
Type | NatA | NatB | NatC | NatD | NatE |
---|---|---|---|---|---|
Original | |||||
Catalytic subunit | Ard1p | Nat3p | Mak3p | Nat4p | Nat5p |
Auxiliary subunit | Nat1p | Mdm20p | Mak10p | † | |
Mak31p | |||||
Revised | |||||
Catalytic subunit | Naa10p | Naa20p | Naa30p | Naa40p | Naa50p |
Auxiliary subunit | Naa15p | Naa25p | Naa35p | † | |
Naa38p | |||||
Number of yeast substrates | ~2,000 | ~1,000 | ~250 | 2? | ? |
Substrates* | Ser- | Met-Glu- | Met-Ile- | Ser-Gly-etc- | ? |
Ala- | Met-Asp- | Met-Leu- | |||
Gly- | Met-Asn- | Met-Trp- | |||
Thr- | Met-Phe- | ||||
Val-‡ | |||||
Cys-¶ | |||||
------------2 to 8 amino acids----------- | 30–50 a. a | ? |