Table 1 Number of significant markers identified by the simultaneous analysis and markers with extreme effect sizes
Chromosome number | Number of SNPs | Number of significant SNPs | Markers with largest risk and protective effects | |||
|---|---|---|---|---|---|---|
| Â | Â | Â | Largest risk effect | Largest protective effect | ||
| Â | Â | Â | Marker | Effect size | Marker | Effect size |
1 | 40929 | 142 | rs7519615 | 1.73638 | rs2275864 | -1.41482 |
2 | 44090 | 140 | rs655783 | 0.91779 | rs938869 | -2.3145 |
3 | 36690 | 138 | rs7616866 | 202.447 | rs9288967 | -4.23478 |
4 | 32628 | 133 | rs768063 | 155.04 | rs6816684 | -2.31044 |
5 | 33612 | 90 | rs344156 | 1.46745 | rs6899062 | -1.68164 |
6 | 35574 | 82 | rs6935937 | 3.06767 | rs1856363 | -2.18496 |
7 | 29244 | 130 | rs9632680 | 96.105 | rs4732523 | -2.41344 |
8 | 30990 | 130 | rs7006628 | 0.577914 | rs2853259 | -1.50527 |
9 | 26128 | 125 | rs6478815 | 154.845 | rs1387292 | -3.12822 |
10 | 28331 | 131 | rs2388121 | 0.777184 | rs1909668 | -1.36459 |
11 | 26477 | 119 | rs1879445 | 123.081 | rs7932437 | -6.04313 |
12 | 26365 | 129 | rs1146114 | 1.43868 | rs7300982 | -1.59685 |
13 | 20242 | 129 | rs2323883 | 4.76091 | rs9740397 | -3.53682 |
14 | 17951 | 124 | rs4296166 | 1.53678 | rs4983565 | -2.02512 |
15 | 16166 | 121 | rs7183817 | 0.814795 | rs3743372 | -2.60765 |
16 | 16460 | 111 | rs4238802 | 0.66247 | rs4783187 | -1.98159 |
17 | 14027 | 123 | rs2880328 | 92.8919 | rs9747823 | -1.31507 |
18 | 16450 | 123 | rs2303508 | 78.2526 | rs1982040 | -2.32656 |
19 | 9236 | 101 | rs3810256 | 1.11899 | rs10404348 | -3.04764 |
20 | 13843 | 114 | rs6513195 | 3.13637 | rs6138601 | -4.63256 |
21 | 8051 | 102 | rs2823819 | 0.971309 | rs1539902 | -1.08918 |
22 | 8205 | 90 | rs761917 | 1.46745 | rs17406434 | -1.68164 |
Total | 531689 | 2627 | Â | Â | Â | Â |