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Table 1 Sample characteristicsa

From: Genome-wide association analysis of cardiovascular-related quantitative traits in the Framingham Heart Study

Variable Exam 1 Exam 3 Exam 5 Exam 7
Examinedb 1659 (100)a 1451 (87.5) 1563 (94.2) 1597 (96.3)
Exam dates 1971 to 1975 1983 to 1987 1991 to 1995 1998 to 2001
Males 754 (45.4) 667 (46.0) 711 (45.5) 724 (45.3)
Age, years 34.8 ± 9.0 47.3 ± 9.0 54.3 ± 8.9 61.0 ± 8.9
BMI, kg/m2 25.0 ± 4.1 25.9 ± 4.6 27.2 ± 4.7 27.9 ± 5.2
SBP, mm Hg 118.9 ± 14.0
119.1 ± 14.2 d
122.3 ± 16.0
123.6 ± 17.3
124.7 ± 18.7
126.3 ± 20.0
126.3 ± 18.8
129.4 ± 20.5
Hypertension medication 30 (1.8) 189 (13.0) 251 (16.1) 502 (31.4)
HDL, mg/dL 51.5 ± 14.4
51.5 ± 14.4
52.0 ± 14.8
52.0 ± 14.8
50.5 ± 15.0
50.4 ± 15.1
54.5 ± 17.0
54.1 ± 17.2
LDL, mg/dL 123.2 ± 34.3
123.4 ± 34.7
136.7 ± 36.3
137.1 ± 36.9
126.3 ± 32.4
129.4 ± 35.3
119.8 ± 31.6
128.5 ± 32.8
TG, mg/dL 83.6 ± 62.7
83.7 ± 62.2
114.4 ± 128.4
114.6 ± 128.6
145.4 ± 119.3
147.3 ± 120.3
135.8 ± 86.8
140.8 ± 88.8
Cholesterol medication 7 (0.4) 14 (1.0) 117 (7.5) 321 (20.1)
Smokers 654 (39.6) 380 (26.2) 269 (17.2) 206 (12.9)
Diabetesc 175 (10.5)    
  1. aValues are mean ± standard deviation for quantitative variables, and count (%) for qualitative variables.
  2. bIndividuals with a recorded age at exam.
  3. cIndividuals who developed diabetes at any point during the study.
  4. dValues in italics are means and standard deviations after adjustment for medication use.