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Table 2 p-Values of autosomal SNPs on chromosome 8 using (1) Offspring Cohort and (2) Original and Offspring Cohort

From: Testing for genetic association taking into account phenotypic information of relatives

  (1) Offspring Cohort (2) Nuclear family
SNP CAa MCA GEE gMQLSb CAa MCA GEE gMQLSb
RS17094201 7.76 × 10-5 1.27 × 10-4 4.40 × 10-5 9.80 × 10-5 1.16 × 10-5 2.22 × 10-5 1.23 × 10-5 1.05 × 10-5
RS12549036 1.90 × 10-4 2.96 × 10-4 8.62 × 10-4 2.65 × 10-4 8.75 × 10-5 1.48 × 10-4 2.15 × 10-4 8.46 × 10-5
RS4961118 2.33 × 10-3 3.15 × 10-3 2.86 × 10-3 2.10 × 10-3 1.67 × 10-4 2.71 × 10-4 3.80 × 10-4 9.93 × 10-5
RS6586789 4.92 × 10-3 6.38 × 10-3 5.54 × 10-3 5.01 × 10-3 1.47 × 10-4 2.40 × 10-4 1.91 × 10-4 1.23 × 10-4
RS16920160 2.27 × 10-4 3.49 × 10-4 5.70 × 10-4 7.94 × 10-5 5.93 × 10-4 8.89 × 10-4 7.63 × 10-4 1.63 × 10-4
RS3812476 1.80 × 10-3 2.47 × 10-3 3.16 × 10-3 1.02 × 10-3 4.42 × 10-4 6.75 × 10-4 7.14 × 10-4 1.90 × 10-4
RS11989122 4.15 × 10-3 5.43 × 10-3 4.62 × 10-3 4.11 × 10-3 2.62 × 10-4 4.12 × 10-4 2.88 × 10-4 2.09 × 10-4
RS3107646 1.82 × 10-4 2.83 × 10-4 1.37 × 10-4 3.20 × 10-4 3.97 × 10-4 6.11 × 10-4 3.03 × 10-4 4.60 × 10-4
RS2738079 2.68 × 10-3 3.60 × 10-3 4.27 × 10-3 6.79 × 10-3 2.58 × 10-4 4.08 × 10-4 1.34 × 10-4 8.47 × 10-4
RS6980645 2.49 × 10-4 3.82 × 10-4 7.71 × 10-5 5.05 × 10-4 4.00 × 10-4 6.15 × 10-4 4.10 × 10-4 8.70 × 10-4
  1. aStatistically inappropriate test.
  2. bPhenotypic data of un-genotyped individuals were also included.