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Table 2 Test results among polygenes affecting HDL on chromosome 19

From: Family-based genome-wide association study for simulated data of Framingham Heart Study

Model

Position

Intercept

Diet

Sex

Rxa

Age

Smokeb

SNP

SE

p-Value

rs10420985

62,077,748

68.693

0.017

13.519

1.508

0.020

0.656

-1.693

0.457

0.000214

rs8182590

13,282,550

68.691

0.029

13.542

1.478

0.019

0.686

-0.973

0.263

0.000222

rs35150881

2,572,193

68.689

0.023

13.537

1.449

0.019

0.663

-1.727

0.550

0.0017

rs8107007

33,248,124

68.691

0.022

13.548

1.454

0.020

0.651

1.683

0.537

0.001723

rs10403702

44,840,424

68.692

0.021

13.532

1.491

0.020

0.647

5.564

2.199

0.011418

rs7251886

46,880,615

68.687

0.020

13.537

1.501

0.020

0.669

-0.666

0.266

0.012645

rs11673050

35,535,929

68.690

0.019

13.530

1.473

0.020

0.659

-0.505

0.279

0.069854

rs2277987

8,458,273

68.689

0.021

13.549

1.480

0.020

0.658

0.496

0.289

0.08626

rs16989305

49,579,243

68.689

0.023

13.540

1.482

0.020

0.666

4.904

3.111

0.115021

rs16966229

36,924,150

68.687

0.021

13.530

1.461

0.020

0.660

-2.165

1.381

0.117801

rs17620029

24,146,152

68.690

0.019

13.539

1.465

0.020

0.652

-0.390

0.369

0.291036

rs3786501

49,691,015

68.691

0.021

13.536

1.473

0.020

0.656

0.217

0.314

0.490909

rs11085876

13,947,513

68.689

0.020

13.540

1.467

0.020

0.655

-0.164

0.273

0.547852

rs17716486

34,455,727

68.690

0.020

13.539

1.478

0.020

0.655

-0.204

0.376

0.586957

rs599458

20,792,763

68.689

0.021

13.538

1.473

0.020

0.657

0.082

0.454

0.856762

  1. aRx, lipid lowering drug use
  2. bSmoke, smoking status