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Table 1 Estimated FWER and power from the simulated 10,000 replicated data sets

From: Genome-wide association studies of rheumatoid arthritis data via multiple hypothesis testing methods for correlated tests

 

T j in Eq. (1)

T j in Eq. (3)

Sample size

Bonferroni

MC

Bonferroni

p_ACT

N1 = N2 = 100a

    

   FWER

0.013

0.036

0.013

0.038

   Power

0.418

0.556

0.418

0.554

N1 = 100, N2 = 150

    

   FWER

0.023

0.054

0.022

0.053

   Power

0.531

0.648

0.521

0.635

  1. aN1, the number of cases; N2, the number of controls.