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Figure 1 | BMC Proceedings

Figure 1

From: Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes

Figure 1

Path diagram describing growth curve modeling of longitudinal measurements of SBP, HDL, LDL, and TG taken at exams 1, 3, 5, and 7. The environmental and demographic covariates given on both sides of the path diagram represent the time invariant covariates sex, age, baseline BMI, and diabetes status. Genetic covariates represent the ten selected markers. The numbers on the lines connecting these covariates with the intercepts and slopes are percentages of explained variation and correlations. Paths with one arrow indicate causal relationships whereas those with two show correlations. The boxes contain t n values representing time-varying covariates hypertensive and cholesterol treatments as well as number of cigarettes smoked.

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