Table 3 Type I error rates and power over six two-way interaction models
From: Allelic based gene-gene interactions in rheumatoid arthritis
Allele-based method | Genotype-based method | |||||
|---|---|---|---|---|---|---|
Type I error rate | Power | Power | ||||
Model | Score | F -test | Score | F -test | Score | MDR |
Dom ∪ Rec | 1.1 | 1.1 | 17.3 | 16.65 | 9.85 | 6.3 |
Modified | 0.78 | 0.84 | 23.95 | 23.45 | 13.75 | 9.3 |
Dom ∩ Dom | 0.8 | 0.84 | 46.75 | 46.15 | 29.3 | 24.5 |
Rec ∪ Rec | 1.22 | 1.26 | 58.2 | 57.7 | 38.1 | 31.9 |
Threshold | 1 | 1.04 | 92 | 91.75 | 80.45 | 73.45 |
Dom ∩ Rec | 0.92 | 0.94 | 96.45 | 96.3 | 88.95 | 82.6 |