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Table 2 Pathways Utilized for System Model Generation

From: Multi-comparative systems biology analysis reveals time-course biosignatures of in vivo bovine pathway responses to B. melitensis, S. enterica Typhimurium and M. avium paratuberculosis

KEGG ID

Pathway Description

Category

STM

BMEL

MAP

hsa04810

Regulation of actin cytoskeleton

Cell Motility

2.13

3.66

-2.45

hsa04664

Fc epsilon RI signaling

Immune System

1.49

3.8

-2.12

hsa04660

T cell receptor signaling

Immune System

2.58

-1.8

-2.14

hsa04630

Jak-STAT signaling pathway

Signal Transduction

1.72

-1.9

3.2

hsa04620

Toll-like receptor signaling

Immune System

2.75

2.92

2.8

hsa04540

Gap junction

Cell Communication

1.65

2.06

2.6

hsa04512

ECM-receptor interaction

Signaling Molecules/Interaction

-2.86

3.2

2.64

hsa04370

VEGF signaling pathway

Signal Transduction

2.06

4.44

-2.39

hsa04340

Hedgehog signaling pathway

Signal Transduction

1.61

-1.34

2.61

hsa04310

Wnt signaling pathway

Signal Transduction

1.38

-1.49

3.01

hsa04210

Apoptosis

Cell Growth and Death

-2.65

3.72

3.04

hsa04150

mTOR signaling pathway

Signal Transduction

1.71

5.21

2.33

hsa04010

MAPK signaling pathway

Signal Transduction

2.28

-2.07

-2.84

  1. Values shown are the Bayesian z-score for each pathway, within a given organism.