Figure 1

CD4 promoter methylation levels at 5 (A), 10 (B) and 21dpi (C). Pyrosequencing result of the promoter methylation level of CD4 gene before and after MDV infection at different time points. A decrease of promoter methylation level was observed only L7₂ chickens. 5dpi: 5 days post infection; 10dpi: 10 days post infection; 21dpi: 21 days post infection. L6₃.Non: noninfected control of L6₃ chicken; L6₃.Inf: infected L6₃ chicken; L7₂.Non: noninfected control of L6₃ chicken; L6₃.Inf: infected L6₃ chicken. n=4 for each line.