Table 1 Description of the different disposable bioreactors assessed.
From: Disposable bioreactors: from process development to production
Name | Mobius® Cellready3L | Nucleo TM | Cultibag STR TM | Cultibag RM TM | Cultibag Orbital TM β-test |
|---|---|---|---|---|---|
Supplier | Millipore™ | Pierre Guerin ATMI | Sartorius | ||
Agitation type | Marine impeller | Paddle | 2 x 3-blade segment impeller | Move back and forth | Orbital shaking |
Minimum working volume | 1L | 8L | 10L | 5.5L | 25L |
Maximum working volume | 2,5L | 20L | 50L | 20L | 50L |
Oxygen regulation | Micro or marcro sparger | Overlay + Sparger | Overlay + Sparger | Overlay only | Overlay only |
pH regulation with carbon dioxide | Headspace or sparger | Sparger | Sparger | Headspace | Headspace |
Temperature regulation | Blanket | Jacket | Jacket | Blanket | Blanket |