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Table 1 AUC values for models with and without rare variants in the first experiment

From: Disease risk prediction with rare and common variants

Variant selection p-value threshold

Common variants only

Common and rare variants

AUC value difference with 95% confidence interval

0.01

0.8057

0.8088

0.0031 (0.0028, 0.0034)

0.005

0.8063

0.8088

0.0025 (0.0023, 0.0027)

0.001

0.8056

0.8076

0.0020 (0.0019, 0.0021)

5.0 × 10−4

0.8062

0.8080

0.0018 (0.0017, 0.0019)

1.0 × 10−4

0.8075

0.8093

0.0017 (0.0017, 0.0018)

5.0 × 10−5

0.8075

0.8092

0.0017 (0.0017, 0.0018)

1.0 × 10−5

0.8079

0.8096

0.0017 (0.0016, 0.0017)

  1. Prediction models were built on the first phenotype replication.