From: A novel method to detect rare variants using both family and unrelated case-control data
Gene | p-value (Madsen and Browning method) | p-value (our method) |
---|---|---|
AKT3 | 0.173 | 1.0 |
BCL2L11 | 0.0555 | 1.0 |
ELAVL4 | 0.90 | 0.0283 |
HSP90AA1 | 0.737 | 8.63 × 10−6 |
NRAS | 0.459 | 1.0 |
PIK3C2B | 1.48 × 10−5 | 8.67 × 10−10 |
PIK3C3 | 0.796 | 1.0 |
PIK3R3 | 0.732 | 0.236 |
PRKCA | 0.564 | 1.0 |
PRKCB1 | 0.684 | 0.236 |
PTK2 | 0.868 | 1.0 |
PTK2B | 0.433 | 1.0 |
RRAS | 0.480 | 1.0 |
SHC1 | 0.925 | 1.0 |
SOS2 | 0.465 | 1.0 |