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Figure 2 | BMC Proceedings

Figure 2

From: A method to detect single-nucleotide polymorphisms accounting for a linkage signal using covariate-based affected relative pair linkage analysis

Figure 2

Observed LR statistics and theoretical mixture distribution. The density of observed LR statistics from LOD scores using SNPs in noncausal genes is plotted. For the first model without a SNP covariate, the theoretical distribution is a 50:50 mixture of a chi-square distribution with 1 df and a chi-square distribution with 2 df because we have one covariate. For the second model with a SNP covariate, the theoretical distribution is a 50:50 mixture of a chi-square distribution with 2 df and a chi-square distribution with 3 df because we have two covariates. The blue curve is for the observed LR statistics; the black curve is for the theoretical values.

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