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Table 1 Determination of the specific cell growth rate, specific production rate of lactate, ammonium and IFN4N, and specific consumption rate of glucose of CHO-K1 (a) and HEK 293T (b) clones.

From: Differences in the production of hyperglycosylated IFN alpha in CHO and HEK 293 cells

a)
Clones μ(h-1) qIFN
(ng.10-6cell.h-1)
qgluc
(μg.10-6cell.h-1)
qlac
(μg.10-6cell.h-1)
qamon
(nmol.10-6cell.h-1)
P4D3 0,0182 ± 0,002 79 ± 8 36 ± 5 40 ± 5 0,027 ± 0,007
P1E9 0,0196 ± 0,002 35 ± 4 24 ± 4 45 ± 5 0,027 ± 0,003
P2A9 0,0249 ± 0,001 41 ± 4 30 ± 2 31 ± 1 0,014 ± 0,004
P1B6 0,0240 ± 0,002 19 ± 3 26 ± 5 49 ± 5 0,013 ± 0,005
P1B7 0,0191 ± 0,002 41 ± 3 32 ± 4 35 ± 2 0,017 ± 0,006
P1B8 0,0277 ± 0,002 42 ± 3 21 ± 3 34 ± 2 0,015 ± 0,004
b)
Clones μ(h -1 ) q IFN
(ng.10 -6 cell.h -1 )
q gluc
(μg.10 -6 cell.h -1 )
q lac
(μg.10 -6 cell.h -1 )
q amon
(nmol.10 -6 cell.h -1 )
P2A5 0,020 ± 0,001 129 ± 10 56 ± 6 37 ± 4 0,014 ± 0,003
P2C7 0,015 ± 0,002 122 ± 13 62 ± 11 38 ± 3 0,009 ± 0,003
P2G11 0,017 ± 0,002 82 ± 6 47 ± 9 31 ± 3 0,008 ± 0,002
P3B7 0,016 ± 0,002 99 ± 8 55 ± 8 31 ± 3 0,008 ± 0,003
P3H8 0,027 ± 0,001 82 ± 11 46 ± 6 34 ± 3 0,008 ± 0,001
P4B4 0,017 ± 0,002 63 ± 5 61 ± 15 32 ± 3 0,009 ± 0,001