Figure 1

Synergistic induction of apoptosis by co-treatmentAnalysis of apoptotic cells by annexin/PI double-staining using theIN Cell Analyzer 1000. MDA-MB-231 and MCF-7 cells were treatedfor different times with 200 μg/mL FE alone or 200 μg/mL FEin combination with 5 μM CDDP, 10 μM TAM or 2.5 nM TAXOL after 48 h of treatment. All results were obtained from three independent experiments. A significant difference from control is indicated by p < 0.05 (#) or p < 0.01 (##); a significant difference from single treatments is indicated by p < 0.05 (*) or p < 0.01 (**).