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Figure 1 | BMC Proceedings

Figure 1

From: Skin and hair-on-a-chip: Hair and skin assembly versus native skin maintenance in a chip-based perfusion system

Figure 1

Microfluidic device for perfused skin equivalent culture and integrated Microfollicle (A) Dynamic chip-based bioreactor for continuous perfusion culture of skin equivalents with integrated microfollicles. (B) PanCytokeratin immunoflourescent staining of a skin equivalent with an inserted microfollicle. (C-J) In vitro skin equivalents (MatTek) cultured for 7 days in MOC or static conditions with and without subcutaneous tissue (SCT) and compared to ex vivo foreskin. (C-F) H&E staining and (G-J) immunofluorescence staining for epidermal markers Cytokeratin 10 and 15. Dashed lines mark the border between the skin equivalent and the subecuteaneous tissue. Scale bars indicate 100μm.

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BMC Proceedings

ISSN: 1753-6561

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