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Figure 2 | BMC Proceedings

Figure 2

From: The impact of structural diversity and parameterization on maps of the protein universe

Figure 2

Prediction of SCOP annotations by pairwise distances and MPSS proximity. ROC curves indicate the performance of a classifier. The solid black diagonal represents a random classifier; better performing classifiers bend towards the upper left of the plot. Parts (A) and (B) contain ROC curves for prediction of membership in SCOP superfamiles and SCOP familes, respectively. Curves are given for each aligner (CE, Dali, FATCAT), using either raw distances, or proximity within MPSS constructed with either classical MDS or stress majorization. In particular, the plots demonstrate that MPSS distances are never significantly worse than pairwise alignment distances.

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