Figure 1
From: Conceptualization of molecular findings by mining gene annotations
Conceptual Overview of Research. A-C. The ontological structure of the GO, protein annotations, and biomedical literature associated with genes were collected. D. The above information was combined to create an integrated graph (GOGenePubmed) that reflects the relationship among genes, their annotations, and the semantic relationships between GO terms. E. Based on this graph, statistical schemes were designed and simulation experiments were performed to establish statistical models for assessing the functional coherence of gene sets. F-G. When provided with a gene list from experiment (F), the program can be used to search for coherent subsets among the list (G).