Protein Name | PDB ID (_Chain) |
|---|
AIF | 1M6I_A | Â | Â | Â | Â | Â |
AKT1 | 1UNQ_A | 3CQW_A | 3O96_A | Â | Â | Â |
AKT2 | 1MRV_A | 1O6K_A | 1O6L_A | 1P6S_A | Â | Â |
AKT3 | 2X18_A | Â | Â | Â | Â | Â |
APAF1 | 1CY5_A | 1Z6T_A | 2YGS_A | 3IZA_A | 3YGS_C | Â |
BCL-2 | 2W3L_A | 2XA0_A | Â | Â | Â | Â |
BCL-XL | 2B48_A | 3FDL_A | Â | Â | Â | Â |
BID | 2BID_A | 2KBW_B | Â | Â | Â | Â |
Bax | 1F16_A | 2G5B_I | 2XA0_C | 3PK1_B | Â | Â |
CASP3 | 1RHQ_A | 1RHQ_B | 2DKO_A | 2DKO_B | 2J32_A | Â |
CASP6 | 2WDP_A | Â | Â | Â | Â | Â |
CASP7 | 1F1J_A | 1I4O_A | 1I51_A | 1I51_B | 2QL9_A | 2QL9_B |
CASP8 | 1QTN_A | 1QTN_B | 2FUN_B | 3H11_B | Â | Â |
CASP9 | 1JXQ_A | 1NW9_B | 3D9T_C | 3YGS_P | Â | Â |
Calpain1 | 1ZCM_A | Â | Â | Â | Â | Â |
Calpain2 | 1KFU_L | 2NQA_A | Â | Â | Â | Â |
Cn(CHP) | 2E30_A | Â | Â | Â | Â | Â |
Cn(CHP2) | 2BEC_A | Â | Â | Â | Â | Â |
Cn(PPP3CA) | 1AUI_A | 1MF8_A | 2R28_C | 3LL8_A | Â | Â |
Cn(PPP3R1) | 1AUI_B | 1MF8_B | 3LL8_B | Â | Â | Â |
CytC | 1J3S_A | Â | Â | Â | Â | Â |
DFF40 | 1IBX_A | Â | Â | Â | Â | Â |
DFF45 | 1IBX_B | 1IYR_A | Â | Â | Â | Â |
FADD | 1A1W_A | 2GF5_A | 3EZQ_B | Â | Â | Â |
FLIP | 3H11_A | Â | Â | Â | Â | Â |
Fas | 3EWT_E | 3EZQ_A | Â | Â | Â | Â |
IAP(BIRC2) | 3D9T_A | 3M1D_A | 3MUP_A | Â | Â | Â |
IAP(BIRC3) | 2UVL_A | 3EB5_A | 3EB6_A | 3M0A_D | 3M0D_D | Â |
IAP(BIRC4) | 1G73_C | 1I4O_C | 1I51_E | 1NW9_A | 2ECG_A | 2KNA_A |
| Â | 2POI_A | 3CM7_C | Â | Â | Â | Â |
IκBα | 1IKN_D | 1NFI_E |  |  |  |  |
IKK | 2JVX_A | 3BRT_B | 3BRV_B | 3CL3_D | 3FX0_A | Â |
IL-1(A) | 2ILA_A | Â | Â | Â | Â | Â |
IL-1(B) | 1ITB_A | 2NVH_A | 3O4O_A | Â | Â | Â |
IL-1R(1) | 1ITB_B | Â | Â | Â | Â | Â |
IL-1R(RAP) | 3O4O_B | Â | Â | Â | Â | Â |
IL-3 | 1JLI_A | Â | Â | Â | Â | Â |
IL-3R | 1EGJ_A | Â | Â | Â | Â | Â |
IRAK2 | 3MOP_K | Â | Â | Â | Â | Â |
IRAK4 | 2NRU_A | 3MOP_G | Â | Â | Â | Â |
MyD88 | 2JS7_A | 3MOP_A | Â | Â | Â | Â |
NF-κB(NFKB1) | 1IKN_C | 1NFI_B | 1SVC_P | 2DBF_A |  |  |
NF-κB(RELA) | 1IKN_A | 1NFI_A |  |  |  |  |
NGF | 1WWW_V | 2IFG_E | Â | Â | Â | Â |
PI3K(PIK3CA) | 2ENQ_A | 2V1Y_A | 3HHM_A | Â | Â | Â |
PI3K(PIK3CG) | 1E8Y_A | Â | Â | Â | Â | Â |
PI3K(PIK3R1) | 1A0N_A | 1H9O_A | 1PBW_A | 2IUG_A | 2V1Y_B | 3HHM_B |
| Â | 3I5R_A | Â | Â | Â | Â | Â |
PI3K(PIK3R2) | 2KT1_A | 2XS6_A | 3MTT_A | Â | Â | Â |
PRKACA | 3AGM_A | Â | Â | Â | Â | Â |
PRKAR2A | 2IZX_A | Â | Â | Â | Â | Â |
TNFα | 1A8M_A | 4TSV_A |  |  |  |  |
TNF-R1 | 1EXT_A | 1ICH_A | Â | Â | Â | Â |
TP53 | 1AIE_A | 1OLG_A | 1XQH_B | 1YC5_B | 2B3G_B | 2FOO_B |
| Â | 2GS0_B | 2K8F_B | 2VUK_A | 3D06_A | 3DAB_B | 3LW1_P |
TRADD | 1F3V_A | Â | Â | Â | Â | Â |
TRAF2 | 1CZZ_A | 1D00_A | 1F3V_B | 3KNV_A | 3M0A_A | 3M0D_A |
TRAIL | 1D4V_B | 1DG6_A | 1DU3_D | Â | Â | Â |
TRAIL-R | 1D4V_A | 1DU3_A | Â | Â | Â | Â |
TrkA | 1HE7_A | 1SHC_B | 1WWW_X | 2IFG_A | Â | Â |
- The abbreviations used are: AIF, apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1); AKT1, RAC-alpha serine/threonine-protein kinase; AKT2, RAC-beta serine/threonine-protein kinase; AKT3, RAC-gamma serine/threonine-protein kinase; APAF1, apoptotic peptidase activating factor 1; BCL-2, B-cell lymphoma 2; BCL-XL, BCL extra-large; BID, BH3 interacting domain death agonist; Bax, BCL-2-associated × protein; CASP3/6/7/8/9, caspase-3/6/7/8/9; Cn(CHP), calcineurin B homologous protein 1; Cn(CHP2), calcineurin B homologous protein 2; Cn(PPP3CA), protein phosphatase 3 catalytic subunit alpha isoform; Cn(PPP3R1), protein phosphatase 3 regulatory subunit 1; CytC, cytochrome C; DFF40, DNA fragmentation factor, 40kDa, beta polypeptide; DFF45, DNA fragmentation factor, 45kDa, alpha polypeptide; FADD, Fas-associated via death domain; FLIP, FLICE/CASP8 inhibitory protein (CASP8 and FADD-like apoptosis regulator, CFLAR); Fas, tumor necrosis factor receptor (TNF) superfamily member 6; IAP, inhibitor of apoptosis; BIRC2/3/4, baculoviral IAP repeat-containing protein 2/3/4; IκBα, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha; IKK, inhibitor of nuclear factor kappa-B kinase; IL-1(A), interleukin-1 alpha; IL-1(B), interleukin-1 beta; IL-1R(1), type 1 interleukin-1 receptor; IL-1R(RAP), interleukin-1 receptor accessory protein; IL-3, interleukin-3; IL-3R, interleukin-3 receptor; IRAK2/4, interleukin-1 receptor-associated kinase 2/4; MyD88, myeloid differentiation primary response protein MyD88; NF-κB(NFKB1), nuclear factor of kappa light polypeptide gene enhancer in B-cells; NF-κB(RELA), nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; NGF, nerve growth factor (beta polypeptide); PI3K, phosphatidylinositide 3-kinase; PIK3CA, PI3K subunit alpha; PIK3CG, PI3K subunit gamma; PIK3R1, PI3K regulatory subunit alpha; PIK3R2, PI3K regulatory subunit beta; PRKACA, cyclic adenosine monophosphate (cAMP)-dependent protein kinase catalytic subunit alpha; PRKAR2A, cAMP-dependent protein kinase type II-alpha regulatory subunit; TNFα, tumor necrosis factor; TNF-R1, TNF receptor superfamily member 1A; TP53, cellular tumor antigen p53; TRADD, TNF receptor type 1-associated death domain protein; TRAF2, TNF receptor-associated factor 2; TRAIL, TNF receptor superfamily member 10; TRAIL-R, TNF receptor superfamily member 10B; TrkA, neurotrophic tyrosine kinase receptor type 1.
