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Table 1 Likelihood ratio tests of gene pathways.Results of likelihood ratio test using the pathway-specific variance component term h g p 2 . The table only shows pathways with p-values lower than 0.01.

From: Pedigree-based random effect tests to screen gene pathways

Pathway # Causal genes Variance explained h r 2 h r 2 pvalue h g p 2 h g p 2 pvalue
CAUSAL_SET 15 0.2151 0.141 0.0019184 0.095 0.0000002
Cytokine_interaction 2 0.032 0.127 0.0130248 0.131 0.0006748
Glutathione_metabolism 2 0.027 0.221 0.0000136 0.074 0.00306
CAUSAL_1_to_9 1 0.0779 0.248 0.0000019 0.039 0.004348
E. coli_infection 0 0 0.244 0.0000099 0.051 0.0081785
CAUSAL_1_to_49 1 0.0779 0.265 0.0000131 0.038 0.178527