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Table 5 The top 10 gene sets/pathways from c2 curated gene sets ranked by FDR q values for DBP

From: Pathway-based analysis of rare and common variants to test for association with blood pressure

Pathway name

No. genes*

ES

NES

FDR

qvalue

PHONG_TNF_RESPONSE_VIA_P38_COMPLETE

13

0.583

1.743

0.580

DELYS_THYROID_CANCER_DN

11

0.612

1.748

0.599

CORRE_MULTIPLE_MYELOMA_DN

3

0.897

1.733

0.603

SHEPARD_BMYB_MORPHOLINO_UP

10

0.609

1.712

0.617

LI_INDUCED_T_TO_NATURAL_KILLER_UP

17

0.537

1.724

0.617

WILCOX_PRESPONSE_TO_ROGESTERONE_UP

6

0.705

1.700

0.621

WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN

13

0.562

1.674

0.632

KEGG_RENIN_ANGIOTENSIN_SYSTEM

3

0.932

1.761

0.632

OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN

11

0.605

1.751

0.633

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

16

0.535

1.685

0.644

  1. *Number of genes on chromosome 3